Emmanuel N. Agomuo
Research by emmanuel n. agomuo
Ameliorative Potential of Aqueous Leaf Extract of Vernonia Amygdalina (Bitter Leaf) on Selected Renal and Hematological Parameters of Rats Exposed to Premium Motor Spirit (PMS)
The ameliorative potential of aqueous leaf extract of Vernonia amygdalina (bitter leaf) on selected renal and hematological parameters of rats exposed to premium motor spirit (PMS) was investigated using standard analytical methods. Thirty-six healthy albino rats weighing 75-200 g was purchased and housed in plastic cages of six groups with six rats each. Improvised method of nose inhalation was adopted for exposure to PMS. Rats fed with normal rat chow constituted the group A...
Read more →Antidiabetic Potential of Methanolic Extract of Newbouldia laevis (Ogirisi) Leaves in Hyperglycemic Wistar Rats
Ideal management of prolonged hyperglycaemia presents both micro and macro vascular complications, a leading cause of morbidity and mortality in diabetic subjects. This study was under taken to give credence to the traditional use of Newbouldia laevis (Ogirisi) leaves in the treatment of diabetes mellitus (DM). Alloxan monohydrate (140 mg/kg) was administered to male wistar rats via the intra-peritoneal route. The oral LD50 of the methanoic extract of N. laevis was >1200 mg/kg. The normal male...
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